Neurocience of psychoactive substance use and dependence / WHO - World Health Organization ; foreword Lee Jong-Wook - xix, 264 p. : il. ; 24 x 16 cm.

Foreword / Lee Jong-wook, director general WHO -- Introduction -- Structure of the report -- Psychoactive subsances and their sociolegal status -- Global use of psychoactive subsances -- Adverse effects of psychoacive substances and their mechanisms of action -- Substance dependence in relation to neuroscience -- The burden of harm to health from psychoactive substance use -- Brain Mechanisms: Neurobiology and Neuroanatomy -- Organization of the brain -- The neuron -- Neurotransmission -- Receptors -- Neurotransmitters Genes -- Cellular and neuronal effects of psychoactive substances -- Biobehavioural processes Underlying Dependence -- Defining terms -- Drug reward alone does not explain drug dependence -- Dopamine and reinfocement learning -- Dopamine and incentive sensitization -- Psychopharmacology of Dependence for Different Drug Classes -- Alcohol (ethanol) -- Sedatives and hypnotics -- Tobacco -- Opioids -- Cannabinoids Cocaine (hydrochloride and crack) -- Amphetamines -- Ecstasy -- Volatile solvents -- Hallucinogens -- Genetic Basis of Substance Dependence -- Genetics of tobacco dependence -- Genetics of alcohol dependence -- Genetics of opioid dependence -- Genetics of the combined risk of dependence on tobacco, alcohol, opioids and other psychoactive substances -- Confounding issues in linkage and candidate gene studies -- Methodological issues -- Future directions -- Social and cultural aspects -- Concurrent Disorders -- Hypotheses that may Neurocience of psychoactive substance use and dependence / WHO - World Health Organization ; foreword Lee Neurocience of psychoactive substance use and dependence / WHO - World Health Organization ; foreword Lee for Public Health Policy -- Index --

92-4-156235-8 -- 978-92-4-156235-5


Drogas psicotropicas--farmacología
Cerebro -- efectos de la drogas
Psicofarmacologia
Desórdenes--sustancia--Relacionados--psicopatologia
Salud
Medicina

615.788 / W551n

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