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020 _a92-4-156235-8 -- 978-92-4-156235-5
082 0 4 _a615.788 / W551n
110 1 _aWHO - World Health Organization
_994155
245 1 0 _aNeurocience of psychoactive substance use and dependence / WHO - World Health Organization ; foreword Lee
245 1 0 _aJong-Wook
264 _aGeneva : WHO - World Health Organization, 2004
300 _axix, 264 p. : il. ; 24 x 16 cm.
505 0 0 _aForeword / Lee Jong-wook, director general WHO -- Introduction -- Structure of the report -- Psychoactive
505 0 0 _asubsances and their sociolegal status -- Global use of psychoactive subsances -- Adverse effects of
505 0 0 _apsychoacive substances and their mechanisms of action -- Substance dependence in relation to neuroscience --
505 0 0 _aThe burden of harm to health from psychoactive substance use -- Brain Mechanisms: Neurobiology and
505 0 0 _aNeuroanatomy -- Organization of the brain -- The neuron -- Neurotransmission -- Receptors -- Neurotransmitters
505 0 0 _a-- Genes -- Cellular and neuronal effects of psychoactive substances -- Biobehavioural processes Underlying
505 0 0 _aDependence -- Defining terms -- Drug reward alone does not explain drug dependence -- Dopamine and
505 0 0 _areinfocement learning -- Dopamine and incentive sensitization -- Psychopharmacology of Dependence for
505 0 0 _aDifferent Drug Classes -- Alcohol (ethanol) -- Sedatives and hypnotics -- Tobacco -- Opioids -- Cannabinoids
505 0 0 _a-- Cocaine (hydrochloride and crack) -- Amphetamines -- Ecstasy -- Volatile solvents -- Hallucinogens --
505 0 0 _aGenetic Basis of Substance Dependence -- Genetics of tobacco dependence -- Genetics of alcohol dependence --
505 0 0 _aGenetics of opioid dependence -- Genetics of the combined risk of dependence on tobacco, alcohol, opioids and
505 0 0 _aother psychoactive substances -- Confounding issues in linkage and candidate gene studies -- Methodological
505 0 0 _aissues -- Future directions -- Social and cultural aspects -- Concurrent Disorders -- Hypotheses that may
505 0 0 _aNeurocience of psychoactive substance use and dependence / WHO - World Health Organization ; foreword Lee
505 0 0 _aNeurocience of psychoactive substance use and dependence / WHO - World Health Organization ; foreword Lee
505 0 0 _afor Public Health Policy -- Index --
650 1 4 _aDrogas psicotropicas
_xfarmacología
_9107338
650 1 4 _aCerebro -- efectos de la drogas
_9102919
650 1 4 _aPsicofarmacologia
_9129349
650 1 4 _aDesórdenes
_xsustancia
_xRelacionados
_xpsicopatologia
_9106599
650 1 4 _aSalud
_9130891
650 1 4 _aMedicina
_9115965
700 1 _aJong-wook, Lee
_e prólogo
_951807
710 1 _aOMS - Organización Mundial de la Salud
_993453
999 _c24943
_d24943