Chemical-specific adjustment factors for interspecies differences and human variability : guidance document for use of data in dose/concentration-response assessment / IPCS, International Programme on Chemical Safety, IOMC, Inter-Organization Programme for the Sound Management of Chemicals
By: IPCS - International Programme on Chemical Safety.
Contributor(s): WHO - World Health Organization | IOMC - Inter-Organization Programme for the Sound Management of Chemicals | Programa Internacional Sobre Seguridad de los Productos Químicos | OMS - Organización Mundial de la Salud (Ginebra) | IPCS Workshop on Incorporating Uncertainty and Variability into Risk Assessment (2000 : Berlin, Germany).
Series: IPCS - harmonization project document no. 2.Geneva : World Health Organization, 2005 Description: iii, 96 p.ISBN: 92-4-154678-6 -- 978-92-4-154678-2.Subject(s): Productos químicos | Toxicidad de los productos químicos | Efectos nocivos | Variación (genética) | Especificidad de la especie | Estándares del gravamen de riesgo | Salud | MedicinaDDC classification: 615.902 / Hp002 Acceso electrónico: http://whqlibdoc.who.int/publications/2005/9241546786_eng.pdfItem type | Current location | Collection | Call number | Vol info | Copy number | Status | Notes | Date due | Barcode | Item holds |
---|---|---|---|---|---|---|---|---|---|---|
Libros | Biblioteca Ciencias de la Salud | FONDO BIBL | 615.902 / Hp002 (Browse shelf) | 8001 | 1 | Available | DO | 8300004507 |
Browsing Biblioteca Ciencias de la Salud Shelves Close shelf browser
Published under the joint sponsorship of the United Nations Environment Programme, the International Labour
Organization, and the World Health Organization, and produced within the framework of the Inter-Organizational
Programme for the Sound Management of Chemicals. Publicado bajo patrocinio común del programa del
ambiente de Naciones Unidas, de la organización de trabajo internacional, y de la Organización Mundial de la
Salud, y producido en el marco del programa interorganizacional para la gerencia sana de productos químicos.
Introduction: Objetives -- Chemical-specific adjustment factors and risk assessment -- Background --
Framework for development of chemical-specific adjustment factors -- Development of default subfactors for
toxicokinetic and toxicodynamic aspects -- Separation of the overall process producing toxicity into
toxicokinetics and toxicodynamics within the context of chemical-specific adjustment factors -- Calculacion of
the composite uncertainty factor -- Guidance for the use of data in development of chemical specific
adjustment factors for interpecies differences and human variability -- Data for the development of a
chemical-specific adjustment factor for interspecies differences in toxicokinetics (AKaf) -- Data for the
development of a chemical-specific adjustment factor for interspecies differences in toxicodynamics (ADaf) --
Data for the development of a chemical-specific adjustment factor for human variability in toxicokinetics
(HKaf) -- Data for the development of a chemical-specifric adjustment factor for human variability in
toxicodynamics (ADaf) -- References -- Case-studies -- Glossary of terms --
Existe también en medio magnético en la Biblioteca Electrónica de la Facultad de Salud
Acceso electrónico: http://whqlibdoc.who.int/publications/2005/9241546786_eng.pdf
There are no comments for this item.